• A PRELIMINARY STUDY ON THE ISOLATION AND DENTIFICATION OF ESBL-PRODUCING SALMONELLA AND ITS ANTIBIOGRAM USING CERTAIN SEED EXTRACTS

Abstract

Salmonellosis ranges clinically from the Salmonella gastroenteritis to enteric fever which are life-threatening febrile systemic illness requiring prompt antibiotic therapy. It is endemic in many developing countries with poor sanitary conditions, but emerges sporadically as a serious public health threat in developed countries. Enteric fever is a growing concern worldwide. World Health Organization (WHO) estimates that there are about 22 million cases of typhoid fever worldwide every year. Antibiotic therapy is useful in resolving signs and symptoms and can be considered in an attempt to eliminate the carrier state. The choice of antibiotics is dependent on the susceptibility of the organism.

Multidrug-resistant isolates of Salmonella typhi are common the results obtained in the present investigation of 25 samples collected all the isolates were identified as Salmonella typhi as they are enriched with selenite F broth and  based on their morphology, cultural and biochemical characteristics. Salmonellosis ranges clinically from the Salmonella gastroenteritis to enteric fever which are life-threatening febrile systemic illness requiring prompt antibiotic therapy. It is endemic in many developing countries with poor sanitary conditions, but emerges sporadically as a serious public health threat in developed countries. β-lactamases are enzymes produced by some bacteria and are responsible for their resistance to β-lactam antibiotics like Penicillins, Cephalosporins, Cephamycins and Carbapenems.