• SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF 5-METHYL-N-ARYL SUBSTITUTED OXAZOLIDINE DIONE DERIVATIVES

V. Shankarananth*, D. Ranganayakulu, C. Sridhar, K. K. Rajasekhar

Abstract


A Convenient high yield one pot methodology for the synthesis of pharmaceutically interesting 5-methyl-N-aryl substituted oxazolidine-2, 4-dione derivatives is described. The structures of compounds were established on the basis of IR, GC-MS and NMR spectral data. The title compounds were investigated for antitubercular activity. The tested compounds exhibited good antitubercular activity as compared to standard drugs.


Keywords


Synthesis,5-methyl-N-aryl substituted oxazolidine-2,4 dione, antitubercular activity.

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