• A SYNCHRONISED STUDY OF THE DIAGNOSTIC ROLE AND SPECIFICITY OF CARDIAC TROPONIN –T IN EARLY DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION

Abstract

The present study was carried out to assess the role of cardiac troponin-T (CTn-T) in one hundred suspected cases of acute myocardial infarction (AMI), admitted in Medical Colleges of North East India and Nepal. The provisional diagnosis of AMI was done on the basis of the history, chest pain, clinical findings and ECG changes. The rapid cardiac troponin-T test (CTn-T) has 100% specificity for AMI whereas CK-MB and LDH have specificities of 80% and 60% respectively. The CTn-T has diagnostic efficiency of 92% for AMI but ECG has only 69% sensitivity and 80% specificity. The overall dii\gnostic efficacy of c.ardiac troponin-T is higher than• thal of CKMB, LDH and ECG (94% versus 92%, 91 % and 72%). The CTn-T test is a superior and better diagnostic tool for all the cases of AMI and ACS, where ECG changes are non-diagnostic and inconclusive. The cardiac troponin-T test, over and above CKMB, LDH and ECG is the1efcre, a valid compliment in early and proper diagnosis of AMI patients.