• EFFECTS OF CARVACROL COMPOUND FROM ORIGANUM VULGARE AGAINST PATHOGENS ISOLATED FROM DIABETIC FOOT INFECTION

Abstract

Diabetes mellitus is a metabolic disorder characterized by the presence of hyperglycemia due to defective insulin secretion, defective insulin action or both. The chronic hyperglycemia of diabetes is associated with relatively specific long-term micro vascular complications affecting the eyes, kidneys and nerves, as well as an increased risk for cardiovascular disease. Diabetic foot infections are infections that can develop in the skin, muscles or bones of the foot as a result of nerve damage and poor circulation that is associated with diabetes. Diabetes mellitus is a disorder that primarily affects the microvascular circulation. Collection of sample diabetic patients included in this study was of age group (35-45).Commercial compound Carvacrol an active medicinal plant in Origanum vulgare was bought from Aroma product Pvt.Ltd, Chennai in Tamil Nadu. The foot sample of both sexes were collected from government hospitals in kanchipuram, a sterile swab was used for collecting sample from diabetic patients study in sample processing, Microscopic examination, Antibiotic sensitivity test, Statistical analysis, the samples were processed according to the standard microbiological techniques the Micro organisms were isolate from pus culture statistical analysis was done. Staphylococcus aureus was the predominant organism among the isolation the gram negative organism Pseudomonas aeruginosa was predominant other organism included in our study was Escherichia coli and Proteus mirabilis, Aspergillus fumigates, Candida albicans.